Hemoglobin-Based Oxygen Carriers as Red Cell Substitutes and Oxygen Therapeutics (Hardcover)

Hemoglobin-Based Oxygen Carriers as Red Cell Substitutes and Oxygen Therapeutics By Hae Won Kim (Editor), A. Gerson Greenburg (Editor) Cover Image

Hemoglobin-Based Oxygen Carriers as Red Cell Substitutes and Oxygen Therapeutics (Hardcover)

By Hae Won Kim (Editor), A. Gerson Greenburg (Editor)

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Brief historical account of HBOC development.- Physiology of respiration.- Oxygen transport to tissues.- Pathophysiology of acute anemia.- Global blood safety and need for safe blood supply.- Blood transfusion and its limitations.- Scientific basis and design of HBOCs.- HBOCs: a regulatory perspective.- Current HBOC products in development.- Clinical indications and clinical trials of HBOCs.- HBOCs and adverse events observed in clinical trials.- HBOC-mediated vasoactivity and hypertension.- HBOC and oxygen and nitrogen radical mediated toxicity.- HBOCs and clinical laboratory interference.- Animal models for HBOC studies.- New emerging Technologies for universal RBCs.- Future prospects.

Product Details ISBN: 9783642407161
ISBN-10: 3642407161
Publisher: Springer
Publication Date: January 9th, 2014
Pages: 746
Language: English